Nathan Croft PhD, MRes, BSc

Nathan completed his Ph.D. in mid-2009 at the University of Birmingham, UK, studying immune evasion by Epstein-Barr Virus. Thereafter, he joined the group of Tony Purcell at the University of Melbourne, transitioning to Monash University in 2012. Nathan's research is focused on understanding how different aspects of the MHC antigen processing pathway impact T cell immunity to pathogens and tumors, with a specific emphasis on how the abundance of MHC peptides plays a role in driving the magnitude and efficacy of T cell responses. In conjunction with this work, Dr. Croft is engaged in mapping the peptide repertoires of healthy and pathogen-infected cell lines, as well as cells and tissues of tumor origin. Together this work strives to develop novel bioinformatics and data repositories that will model and predict the generation of peptide epitopes and their potential immunogenicity.