Dr Congreve has an excellent track record in drug discovery and development in both big pharma and biotechnology settings. He began his career with Glaxo in 1993 and worked on a range of GPCR, other receptor and enzyme projects both in lead optimisation and hit-to-lead phases, a number of which led successfully to clinical candidates. He later moved to manage the Glaxo Wellcome Chemistry Laboratory in Cambridge, working on solid phase library technologies and initiating a number of collaborations with academics across the UK.
Dr Congreve joins Heptares from Astex Therapeutics where he was Director of Chemistry. He played a critical role in establishing the team which developed and validated fragment-based drug discovery as a new approach to structure-based drug design and lead identification. The platform delivered five preclinical and clinical candidates in collaborative and in-house projects.
Dr Congreve obtained a BSc in Biological Chemistry from Leicester University and a PhD in Synthetic Chemistry from Cambridge University. He is co-author of more than 50 publications and co-inventor on more than 30 patent filings.
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