Max Crispin is Director of the Institute for Life Sciences and Professor of Glycobiology at the University of Southampton. Max runs the Glycoprotein Therapeutics Laboratory (within the School of Biological Sciences) which is predominantly focused on developing anti-viral vaccines and new antibody-based therapies against cancer.
In the Glycoprotein Therapeutics Laboratory, we exploit the glycan modifications of proteins in the design of vaccine candidates and glycoprotein-based therapeutics. We have a particular interest in vaccine design against the Human Immunodeficiency Virus (HIV) and in the development of novel antibody-based cancer therapeutics. This involves understanding how glycans impact protein and viral function, how they are structured, and how they can be manipulated for therapeutic applications.