Matthew Lamarche PhD

Matt obtained his bachelor’s degree in biochemistry from the University of Notre Dame in 1997, and as an undergraduate working in the labs of Christopher T. Walsh at Harvard Medical School. In 2002, Matt earned a PhD from the University of Pennsylvania under the guidance of Professor Amos B. Smith, III. In 2002, Matt joined Millennium Pharmaceuticals in Cambridge, MA as a medicinal chemist, and in 2005 moved to Novartis.

His career research has spanned several therapeutic areas such as metabolism, infectious disease and oncology. Most recently, Matt led the SHP2 project in identifying molecules that allosterically inhibit SHP2 phosphatase for cancer, currently in clinical studies. Matt has driven 4 NCEs into clinical study, has >60 publications, and is the chair of the 2019 GRC on Natural Products and Bioactive Compounds. Matt is a native of the Boston area and currently resides there with his family.