Massimo Gadina PhD

Dr. Massimo Gadina is the Chief of the Translational Immunology Section at the National Institute of Arthritis, Musculoskeletal and Skin Diseases at the NIH. Prior to this appointment, he was Senior Lecturer (tenured) at the School of Medicine, Dentistry and Biomedical Sciences, The Queen’s University of Belfast, Northern Ireland (UK). He is currently serving as Editor in Chief of the Journal “Inflammation”

Dr. Gadina’s research interests are focused on the biology of cytokines, their relative signaling pathways, and specifically on the role of these molecules in driving immune-mediated diseases. He has been involved in the development of a new class of drugs used to treat autoimmune and inflammatory diseases known as JAK inhibitors.

Gadina group has also been investigating the effects of the JAK inhibitors on human immune cells as well as the demonstration of in vivo efficacy in animal models of autoimmunity. He has also been involved in several translational studies that have defined the molecular basis of several major Mendelian autoinflammatory and immunological diseases.