Martin S. Denzel PhD

Martin S. Denzel is a Principal Investigator at the AltosLabs. He studies the molecular underpinnings of longevity using high-resolution genetic screens in multiple organisms, including Worms and mice. Dr. Denzel investigates energy and protein metabolism as well as conserved stress signaling pathways that can be tuned to extend survival. To elucidate underlying molecular mechanisms Dr. Denzel employs structural biology approaches. Recently, his team showed that inhibition of the integrated stress response (ISR) extends lifespan. For his basic research, Dr. Denzel received support from all major European and German funding organizations, including EMBO and ERC. He aims to apply basic research and co-founded the start-up company Acus Laboratories.