Mark J. Truty MD, MSc, FACS

Mark J. Truty, M.D., performs clinical and translational research in pancreatic, hepatobiliary and gastrointestinal cancers. His clinical research is in the multidisciplinary surgical treatment of advanced gastrointestinal cancers, with a focus on novel preoperative therapies. He also serves as an institutional principal investigator on clinical trials.

Dr. Truty's translational and basic science work focuses on development of personalized animal models of individual patient tumors removed at surgery or at biopsy, with the goal of identifying effective screening and therapeutic biomarkers, assessing preclinical chemotherapeutic drug efficacy, and modeling of ideal treatment sequencing.

Dr. Truty is evaluating diagnostic and treatment strategies to improve perioperative outcomes of gastrointestinal surgical patients in an effort to minimize complications after surgery. Specifically, he is looking at inhibition of endogenous pancreaticoenteric catalytic enzymes that he has found are linked to a variety of disorders.