Mark Currie PhD

Mark Currie has led Ironwood’s R&D efforts since joining Ironwood in 2002. He led the discovery of the natural hormones (guanylin and uroguanylin) that activate guanylate cyclase‐C (GC‐C), a target thought to be useful in the treatment of a number of gastrointestinal diseases, and he brought a unique understanding of GC‐C pharmacology to Ironwood. This expertise in GC‐C and related cyclic guanosine monophosphate pathways supported our team’s discovery and development of our first medicine.
,br/> Prior to joining Ironwood, Mark directed cardiovascular and central nervous system disease research as vice president of discovery research at Sepracor, Inc. He also initiated, built and led discovery pharmacology and served as director of arthritis and inflammation at Monsanto Company, leading an effort that resulted in marketed Cox‐2 inhibitors for the treatment of pain in humans and animals. Mark earned a Ph.D. in cell biology from the Bowman‐Gray School of Medicine of Wake Forest University and a B.S. in biology from the University of South Alabama.