Marina Cavazzana MD, PhD

Marina Cavazzana is a pediatrician, Professor of Hematology since 2000, Director of the Department of Biotherapy at Necker Hospital, Paris Descartes University. She is the Director of the Inserm / Assistance Publique – Hospitals of Paris GHU Ouest Biotherapy Clinical Investigation Center and leads the research “Human lymphohematopoietic” Laboratory at Imagine Institute.

Her main research and clinical interests are the development of the hematopoietic immune system, and cell and gene therapy for inherited and acquired disease of the hematopoietic system. Her group studies the means to improve the clinical results of hematopoietic stem cell transplantation, crossing HLA-barriers, and the differentiation of mouse and human stem cells towards lymphocyte lineages. She has initiated several clinical trials based on the use of ex vivo gene-modified hematopoietic stem cells to treat patients with inherited disorders, the preliminary clinical results of which are encouraging.