Marc Del Bigio

Dr. Del Bigio holds the Canada Research Chair in Developmental Neuropathology (2004-2017). The broad theme of his work is to understand how insults of various types affect the immature nervous system differently from the mature nervous system. Concurrent studies are conducted using human tissue (especially autopsy material) and animal / cell culture models. Dr. Del Bigio is author of >170 peer reviewed scientific papers. Specific research underway includes: 1) Preclinical studies of pharmacologic therapy for hydrocephalus 2) Pathogenesis of immature brain damage due to hemorrhage 3) Pathology and pathogenesis of brain abnormalities associated with in utero alcohol exposure 4) Mechanical properties of brain tissue at different stages of maturation and in various disease states 5) Pathogenesis of rare brain diseases 6) Human neuropathology in population health (e.g. viral encephalitis, substance abuse)