Leonard H. Augenlicht PhD

Len Augenlicht heads the Colon Program, and serves as Associate Director for Translational Research, of the Albert Einstein Cancer Center. The colon group, located at the Montefiore Medical Center, consists of 5 laboratories headed by independent investigators (L. Augenlicht, A. Velcich, B. Heerdt, J. Mariadason, L. Klampfer and E. Lin) that collaborate on studies focused on mechanisms that establish and maintain normal homeostasis of the intestinal mucosa, perturbations that lead to tumor development, and in translating this research to patient populations for modulation of risk for cancer, early detection of disease, and rational approaches to therapeutic intervention. In addition to grants that fund individual projects of the investigators, the group was designated by the NCI as a Center for the investigation of Nutritional-Genomic Interactions in Cancer, reflecting its focus on genetic mechanisms and their interaction with environmental signals as determinants of disease risk and progression.