Molecular Biology, Immunology and Microbiology Cambridge, England, United Kingdom
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Leo James is a despite extracellular immune surveillance, viral and bacterial pathogens are still able to infect cells. This means each cell must have its own mechanisms for directly restricting pathogen replication. It is this process of intracellular immunity that my lab is interested in. We take a hypothesis-driven approach and investigate infection from both the host and pathogen perspectives. The evolutionary arms race between the two continues to provide some of the most unexpected and fascinating discoveries in biology and these insights form the basis of future medicines and therapies.
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