Lawrence A. Tabak DDS, PhD
Dr. Lawrence Tabak's laboratory studies the functions and biosynthesis of O-glycans. Mucin-glycoproteins are heavily decorated with carbohydrate side-chains, termed O-glycans, which are often clustered within repeating amino acids sequences of the protein (tandem repeats). Functionally, membrane-bound mucins are involved in signal transduction events, whereas secreted mucins contribute to the formation of extracellular matrix or to the gel-like mucus coat which envelopes mucosal surfaces of the body thereby forming the most exterior face of the innate immune system. Although it is known that O-glycans are ubiquitous among proteins, the precise nature of the “O-glycome” remains to be defined. We have approached this by both top-down and bottom-up proteomic studies as well as investigations of the substrate specificities of the multi-gene family of enzymes that are responsible for the formation of O-glycans, the UDP-GalNAc:polypeptide N-Acetylgalactosaminyltransferases (GalNAcTs).
MOC / CME / CE Requirements
Connecticut Medical Examining Board
Connecticut Medical Examining Board accepts the credit courses that are accredited by ACCME and awards AMA PRA Category 1 Credit.
CME Credits Required : 50.00 | Licensing Cycle AMA PRA : 2 Years | Category Credits : 0.00
A minimum of 50 contact hours of qualifying continuing medical education every 2 years commencing on the first date of license renewal;1 contact hour means a minimum of 50 minutes of the continuing education activity once every 6 years.1 CME hour in each of the following topics:
(A) Infectious diseases, including, but not limited to, acquired immune deficiency syndrome and human immunodeficiency virus,
(B) risk management,
(C) sexual assault,
(D) domestic violence,
(E) cultural competency,
(F) behavioral health.
Beginning January 1, 2020, such behavioral health CME must include at least 2 contact hours on diagnosing and treating (i) cognitive conditions, including, but not limited to, Alzheimer’s disease, dementia, delirium, related cognitive impairments, and geriatric depression, or (ii) mental health conditions, including, but not limited to, those common to veterans and family members of veterans such as post-traumatic stress, risk of suicide, depression, and grief. OCC/MOC not accepted as a substitute. The commissioner may grant a waiver for not more than 10 contact hours of CME for physicians who:
(1) engage in activities related to the physician’s service as a member of the Connecticut Medical Examining Board,
(2) engage in activities related to the physician’s service as a member of a medical healing panel, or
(3) assist the state Department of Public Health with its duties to board and commissions (described in Ch. 368a. Sec. 10a-14).