Katharine Orf PhD

Dr. Katharine Orf is a researcher at University College London whose work focuses on gene editing approaches for rare immune disorders. Her doctoral research investigates innovative strategies to correct Activated Phosphoinositide 3-Kinase Delta Syndrome (APDS), a rare inherited immune condition, using advanced base-editing technologies in T cells and haematopoietic stem cells. Her work aims to develop more precise and potentially curative therapies for patients with inborn errors of immunity, contributing to the growing field of translational genetic medicine.