Karolin Luger BS, MS, PhD

Karolin Luger is investigating the structural biology of genome organization. Luger hopes to understand the fundamental impact of chromatin architecture on genome-related processes such as regulated gene transcription, DNA replication, and DNA repair. Research in the Luger Lab focuses on the interaction of nucleosomes with nuclear factors, and on structural and mechanistic aspects of the cellular machinery that assembles and disassembles chromatin during transcription, replication, and DNA repair. The evolution of eukaryotic chromatin structure is investigated through structural studies of archaeal chromatin and chromatin-associated factors.