Julien Seneschal PhD

Julien Seneschal, 35 years old is assistant professor in the department of dermatology and paediatric dermatology at the university hospital in Bordeaux. He has clinical interests in the management of inflammatory skin diseases such as psoriasis, atopic dermatitis, systemic sclerosis, cutaneous lupus and skin reactions associated with the use of biotherapies and small molecules.He is director of the Immunodermatology team in the INSERM 1035 unit with special interests in the comprehension of the immune mechanisms leading to inflammatory skin diseases and vitiligo.

His publications are as follows:
A. Bertolotti, K. Boniface, B. Vergier, D. Mossalayi, A. Taieb, K. Ezzedine, J Seneschal. Type I Interferon signature in the initiation of the immune response in vitiligo. Pigment Cell Melanoma Res. 2014 May : 398-407.
J. Seneschal, X. Jiang, T.S. Kupper : Langerin+ Dermal DC, but not Langerhans cells, are required for effective CD8 mediated immune responses after skin scarification with Vaccinia Virus (VACV). J Invest Dermatol. In press.
A. Diallo, K. Boniface, T. Jouary, J. Seneschal, F. Morice-Picard, S. Prey, M. Cario-André, J. Mazereeuw-Hautier, A. Taieb, K. Ezzedine. Development and validation of the K-VSCOR for scoring Koebner’s phenomenon in vitiligo/non-segmental vitiligo Pigment Cell Melanoma Res. 2013: 402-7
J.Seneschal, R.A.Clark, A. Gehad, Clare M. Baecher-Allan, T.S. Kupper. Human Epidermal Langerhans Cells Maintain Immune Homeostasis in Skin by Activating Skin Resident Regulatory T Cells. Immunity. 2012: 873-84.
H.R Rezvani, N. Ali, M. Serrano-Sanchez, P. Dubus, C. Varon, C. Ged, C. Pain, M Cario-André, J. Seneschal, A. Taieb, H. de Verneuil, F. Mazurier. Loss of epidermal hypoxia-inducible factor-1? accelerates epidermal aging and affects re-epithelialization in human and mouse. J Cell Sci. 2011; 4172-83.
P.Duffau*, J. Seneschal*, C.Nicco*, J.F.Viallard, J.L.Pellegrin, B.Weil, J.F.Moreau, F.Batteux*, P.Blanco*: Modulation of interferon-alpha secretion by activated platelets in systemic lupus erythematous. Sci Transl Med. 2010; 47ra63 * equally contribution.