Speaker Profile
Judith B. Zaugg

Judith B. Zaugg PhD

Bioinformatics
Heidelberg, Baden-Wurttemberg, Germany

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Judith has been a bioinformatics postdoc in the Steinmetz lab at Stanford since 2012. Her main research interest is to understand the genetically determined variability of gene regulation among human individuals, to gain a better molecular understanding of complex genetic traits and diseases. During her Ph.D. at the European Bioinformatics Institute (EMBL-EBI) and Cambridge University with Nick Luscombe, she integrated various ‘omics’ type data sets to uncover several non-canonical gene regulatory mechanisms in yeast, such as gene-looping, nucleosome positioning, and the interplay of non-coding RNA and histone modifications. In her current research at Stanford,

Judith studies the variability of gene regulatory processes across individuals and during development, and how the observed differences can be explained by the underlying genotypes. The regulatory mechanisms she is focusing on include chromatin states, transcription factor binding, three-dimensional DNA conformation, and transcript isoforms. Recent findings from a pilot study in collaboration with Mike Snyder’s group at Stanford revealed a strong genetic basis for differences in chromatin states among individuals.
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