Joseph Dukes PhD

Joseph Dukes joined Enara Bio in 2019 following leadership across research and early development of novel immunotherapies, having led molecules from early discovery and validation through to first-in-human clinical studies. Before joining Enara Bio, Joe spent eight years at Immunocore, developing novel TCR-based bispecific therapeutics. During this time, he established a bespoke, in vitro preclinical approach for generating safety data to de-risk TCR-based therapeutics. In his role as Head of Biology, Joe oversaw TCR discovery, characterisation, and preclinical screening of drug candidates. In addition, Joe was Program Leader for the second TCR-bispecific molecule to enter the clinic, leading cross-functional teams from early discovery in research, through preclinical and clinical development to successful IND/CTA submissions and first-in-human Phase 1 studies. Joe obtained a PhD in Cell Biology and a subsequent post-doctoral fellowship at the University of Bath.