Joseph B. El-khoury MD

Dr. El Khoury’s laboratory focuses on studying the role of macrophages and microglia in Neurodegeneration, host defense and inflammation. We are investigating the mechanisms by which modified-self proteins such as β-amyloid (Aβ) and non-self infectious pathogens (Staphylococcus Aureus and Cryptococcus neoformans) interact with microglia and macrophages, how they activate these cells to produce pro-inflammatory molecules and how microglia and macrophages are recruited to sites of deposition of Aβ and infections.