Joseph Anthony Fraietta PhD

Dr. Joseph Fraietta is T cell biologist with expertise in tumor immunology. He has developed novel approaches for the treatment of cancer through genetic modification of T cells that contributed to the initiation of multiple clinical trials. Dr. Fraietta’s research efforts have been directed towards enhancing the specificity, persistence and efficacy of CAR T cells, developing mechanisms to render T cells resistant to the tumor microenvironment and improving the processes of engineering lymphocytes. His laboratory has been leading initiatives to interrogate cellular products for mechanisms of potency with the objective of predicting clinical responses to these therapies.