Speaker Profile
Jorg Tost

Jorg Tost PhD

Genetics, Research and Clinical Research
Evry, Ile-de-France, France

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Jörg Tost received his PhD in genetics from the University of Saarbrucken (Germany) in 2004 devising novel methods for the analysis of haplotypes and DNA methylation patterns. After a postdoctoral stay in the technology development department of the Center National od Genotypage (CNG, Evry, France), he led the Epigenetics groups from 2006-2012, before becoming Director of Laboratory for Epigenetics and Environment at the Center National of Genotypage (part of the CEA-Institute of Genomics).

The laboratory is involved in the development and application of technologies to analyse DNA methylation, miRNAs and other epigenetic modifications quantitatively at high resolution at target loci and genome-wide using state-of-the-art sequencing technologies as well as the development of bioinformatic tools for the processing of such data.

While initially focussing on the analysis of DNA methylation patterns implicated in tumourigenesis, the laboratory has extended the analysis to immune-related and neurodegenerative diseases and in particular how environmental exposure influences epigenetic profiles. A second research axis investigates novel technologies for the analysis of mutations of clinical relevance present at very low proportions in the analyzed samples and their impact on treatment management.
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