John Dart is a Consultant Ophthalmologist at Moorfields Eye Hospital specialising in infectious and inflammatory Corneal and External Eye Diseases. He is a member of faculty of the NIHR Biomedical Research Centre at Moorfields and the UCL Institute of Ophthalmology, and an Honorary Professor at UCL. His current research is both clinical and laboratory based, with collaborators at UCL, and focused on both scarring conjunctivitis and corneal infection.
Current studies on conjunctival scarring include investigation of the genetic predisposition and basement membrane epitopes in mucous membrane pemphigoid and in vitro translational studies exploring inhibitors of conjunctival scarring. Studies on corneal infection are on Acanthamoeba keratitis (AK), for which he has lead the development of topical biguanide therapy which is progressing through licensing studies, and also identifying the role of the host inflammatory response in AK, using epidemiological genetics.
He graduated from Oxford University, trained in Ophthalmology at the Oxford Eye Hospital and at Moorfields, with fellowships at the Baylor College of Medicine, Houston and at Flinders University, Adelaide. He was a lecturer at the Institute of Ophthalmology from 1984 to 1989 and appointed Hon. Consultant at Moorfields in 1987. He was appointed to the Consultant Staff at Moorfields in 1989 and Hon Professor at UCL in 2011.