Dr. Liu is currently the Deputy Director, Research Programs and the Senior Group Leader, Human Genetics at the Genome Institute of Singapore. Dr. Liu got his PhD on quantitative genetics at Duke University and did his postdoctoral training in the genetics of psychiatric diseases at Columbia University. Dr. Liu’s main research interest is to understand the genetic basis of human disease susceptibility and inheritance. Mainly focusing on complex disease phenotypes, his lab pursues collaborative research to discover genetic variants that influence disease susceptibility, progression and treatment outcome by employing both hypothesis-driven and hypothesis-free strategies for genetic analysis.
His publications are as follows:
Liu H, Irwanto A, Fu X, Yu G, Yu Y, Sun Y, Wang C, Wang Z, Okada Y, Low H, Li Y, Liany H, Chen M, Bao F, Li J, You J, Zhang Q, Liu J, Chu T, Andiappan AK, Wang N, Niu G, Liu D, Yu X, Zhang L, Tian H, Zhou G, Rotzschke O, Chen S, Zhang X, Liu J, Zhang F "Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy." Nat Genet 2015 Mar ; 47(3) : 267-71 Epub 2015 Feb 2.
Yang SK, Hong M, Baek J, Choi H, Zhao W, Jung Y, Haritunians T, Ye BD, Kim KJ, Park SH, Park SK, Yang DH, Dubinsky M, Lee I, McGovern DP, Liu J, Song K "A common missense variant in NUDT15 confers susceptibility to thiopurine-induced leukopenia." Nat Genet 2014 Sep ; 46(9) : 1017-20 Epub 2014 Aug 10
Zhang FR, Liu H, Irwanto A, Fu XA, Li Y, Yu GQ, Yu YX, Chen MF, Low HQ, Li JH, Bao FF, Foo JN, Bei JX, Jia XM, Liu J, Liany H, Wang N, Niu GY, Wang ZZ, Shi BQ, Tian HQ, Liu HX, Ma SS, Zhou Y, You JB, Yang Q, Wang C, Chu TS, Liu DC, Yu XL, Sun YH, Ning Y, Wei ZH, Chen SL, Chen XC, Zhang ZX, Liu YX, Pulit SL, Wu WB, Zheng ZY, Yang RD, Long H, Liu ZS, Wang JQ, Li M, Zhang LH, Wang H, Wang LM, Xiao P, Li JL, Huang ZM, Huang JX, Li Z, Liu J, Xiong L, Yang J, Wang XD, Yu DB, Lu XM, Zhou GZ, Yan LB, Shen JP, Zhang GC, Zeng YX, de Bakker PI, Chen SM, Liu JJ "HLA-B*13:01 and the dapsone hypersensitivity syndrome." N Engl J Med 2013 Oct 24 ; 369(17) : 1620-8.