Speaker Profile
Jeffrey Carroll

Jeffrey Carroll PhD

Neuroscience
Seattle, Washington, United States of America

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Jeffrey Bryan Carroll is an American scientific researcher in the field of Huntington's disease (HD). As a carrier of the abnormal gene that causes HD, he is also a public advocate for families affected by the disease and co-founder of the HD research news platform HDBuzz. His life and work were the subject of a 2011 Gemini award-nominated CBC documentary feature. Carroll is an Associate Professor of neuroscience in the Department of Biology at the University of Washington.

Jeffrey was Born in Seattle on August 18, 1977, to parents Cindy and Jim, Carroll is one of six siblings. He joined the US Army in 1998, serving in Kosovo. While serving in the army, Carroll's mother was diagnosed as suffering from Huntington's disease (HD), a fatal, incurable, genetically inherited neurodegenerative illness. Learning that he and his siblings were each at 50% risk of having inherited the genetic abnormality that causes HD, and having no scientific background, Carroll enrolled in an Army-sponsored basic biology course, initiating a career as a neuroscientist.

On leaving the US Army in 2001, Carroll joined an undergraduate biology program at the University of British Columbia, Vancouver, followed by a doctoral program in UBC's Centre for Molecular Medicine and Therapeutics in the laboratory of Dr Michael Hayden. Carroll gained a PhD in 2010 for his research into Huntington's disease, including work on the YAC128 HD mouse model, the role of caspase 6 in HD, genetic variation in the human HD gene, and the potential of allele-specific gene silencing using antisense oligonucleotides as a treatment for the condition.

As a postdoctoral researcher, Carroll worked in the laboratory of Dr Marcy MacDonald at Harvard University on metabolic abnormalities in Huntington's disease before moving to Western Washington University in 2011 where he is a Visiting Professor in the Department of Psychology and continues to conduct research into Huntington's disease. In 2022, he moved as an Associate Professor at the Department of Neurology at the University of Washington.