Janean E. Holden PhD, RN, FAAN

Janean E. Holden’s preclinical research builds on identifying the mechanisms underlying pain modulation in the spinal cord that alter pain perception in the brain. Specifically, her research is aimed at mechanisms of hypothalamic nociceptive and neuropathic pain modulation in the spinal cord dorsal horn, and includes preliminary work using the chemotherapy agent paclitaxel in a rat model of hypothalamic pain modulation. Dr. Holden’s teaching expertise lies in the area of pathophysiology.  She teaches at both the undergraduate and graduate levels, including an online master’s level pathophysiology class.  She especially enjoys teaching and working with students in her laboratory, and has a dozen graduate and undergraduate students working as research technicians.