James Eric Mcduffie BS, PhD, MBA

Dr. J. Eric McDuffie is heading the Mechanistic & Investigative Toxicology (MIT) team at Janssen’s La Jolla site. He joined Janssen in 2007, after a 7-year tenure at Pfizer’s Ann Arbor and Plymouth, MI sites. At Pfizer, he was responsible for providing investigative pathology and immunotoxicology support for Antibacterial, Cardiovascular/Atherosclerosis, Neuroscience, Dermatology, Inflammation, and Oncology projects.
At Janssen, Dr. McDuffie’s team provides support to early discovery teams and work as part of a global group of preclinical safety assessment scientists to implement discovery toxicology strategies that enable rapid selection and progression of drug candidates to clinical trials, mostly for the Immunology and Neuroscience Therapeutic Areas. Dr. McDuffie has 17 years of experience in preclinical toxicology, including applications of novel toxicity mechanism-based assays and integrated models to support early target safety as well as to investigate potentially translatable organ-specific liabilities for late stage drug candidates.