Ian McCaffery, Ph.D., is Vice President and Head of Oncology Translational Research at Janssen Research and Development, LLC. Ian’s team is responsible for translational research, clinical biomarker discovery and development to support the Oncology Therapeutic Area pipeline. This includes dedicated disease area translational teams and cross-functional biomarker operations and bioinformatics teams. Ian has more than 15 years of experience in the biotechnology industry, leading target, biomarker and companion diagnostic discovery and development programs in research and early/late-stage clinical development. He joined Janssen from Corvus Pharmaceuticals where he established and led the Discovery and Translational Research team focused on immuno-oncology discovery and translational research.
Prior to Corvus, Ian served as Global Head of Companion Diagnostic Development at Genentech, developing, clinically-validating and registering predictive and prognostic diagnostic markers across all therapeutic areas in the Genentech and Roche product development portfolios. Ian joined Genentech from Amgen having served in several roles with increasing responsibility, including as Head of the Oncology Biomarker Development Department in Medical Sciences with accountability for biomarker discovery and development for all research, early and late-stage development programs in oncology. Ian spent his early biotech career at Celera Genomics, using genomic and proteomic tools for target discovery research and drug development in oncology. Ian received his Ph.D. in Biochemistry and Molecular Biology from the University of Leeds, United Kingdom and gained postdoctoral experience at the University of Virginia investigating mechanisms of gene regulation.