Howard Y. Chang MD, PhD

Howard Y. Chang is a Professor of Dermatology at Stanford University. He is a physician-scientist who has trained in genome science. Her research has focused on mechanisms that coordinate the activities of a large number of genes in cell fate control. Made a series of discoveries that introduced the important and pervasive roles of long noncoding RNAs in biological regulation. Her group has substantial experience in epigenetics and RNA biology, including the invention of new methods for epigenomic profiling, mapping RNA occupancy on chromatin, and defining RNA structures genome-wide. Her group pioneered methods to identify key regulators of large-scale transcriptional programs; these methods have been highly fruitful for studies of development, cancer, and aging. The long-term goal of my laboratory is to decipher the regulatory information in the human genome for disease diagnosis and therapy.