Himisha Beltran MD

Dr. Himisha Beltran is a physician-scientist focused on prostate cancer research, and she is the Director of Translational Research in the Department of Medical Oncology at the Dana Farber Cancer Institute. Dr. Beltran and her laboratory are focused on understanding mechanisms of treatment resistance in advanced prostate cancer. In particular, they have developed therapeutic targets and biomarkers for non-androgen receptor-driven prostate cancer, including neuroendocrine prostate cancer (NEPC), an aggressive subtype of castration resistant prostate cancer.

Dr. Beltran has led the molecular characterization of NEPC and has developed patient-derived models to understand the mechanisms underlying AR-independent prostate cancer, the pathogenesis of NEPC, and to develop new therapeutic targets. Dr. Beltran has also developed novel molecular biomarkers to detect NEPC and other emerging resistance subtypes of castration resistant prostate cancer that she will apply to the current platform.