Hideaki Yano PhD

Dr. Hideaki Yano is an assistant professor in the Department of Pharmaceutical Sciences and the Center for Drug Discovery at Northeastern University. Dr. Yano has investigated mechanisms of functional selectivity, allosterism, and superagonism in GPCRs. He is currently examining these themes in the context of dopamine receptor and cannabinoid receptor pharmacology. He has developed tools to study these mechanisms and has identified previously unappreciated forms of signaling bias among G protein subtypes. These biases extend to electrophysiological and behavioral levels, providing a therapeutic proof-of-concept.