Hidde Ploegh is a biochemist who's an area of interest is the immune system. He is known for his analysis of the pathways involved in antigen presentation by-products of the Major histocompatibility complex (MHC).
Ploegh was born in the Netherlands and came to Boston to perform the experimental part of his Ph.D. work under the supervision of Jack Strominger at Harvard University in 1977. He returned to Europe in 1980, and after having held positions in Germany (1980-1984) and the Netherlands (1984-1992) he joined the faculty of MIT as a full professor in 1992. In 1997 he became the incumbent of the Mallinckrodt Professorship in Immunopathology at Harvard Medical School and taught both undergraduate and graduate immunology as the director of the graduate program in immunology. He was recruited back to MIT in 2005. After spending more than 10 years at MIT's Whitehead Institute for Biomedical Research, he joined the Program in Cellular and Molecular Medicine at the Boston Children’s Hospital.
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