Hana Ghanim PhD

Hana Ghanim is a  Graduate Student Researcher in the Porteus Laboratory, Stanford University School of Medicine. Her research focuses on developing gene-editing therapies for genetic diseases, with a particular emphasis on creating a pre-clinical autologous stem cell therapy for X-Linked Agammaglobulinemia (XLA), a rare immunodeficiency disorder. Through the design and optimization of CRISPR-based strategies, she has achieved high-efficiency and precise gene targeting at the BTK locus in human hematopoietic stem and progenitor cells.

Before joining Stanford, Hana worked as a Research Associate at the Gladstone Institutes in the Conklin Laboratory, where she led projects on therapeutic genome editing for inherited cardiomyopathies and co-invented a patent for universal TNNT2 CRISPR guide RNAs. She also developed innovative approaches for generating 3D motor neuron spheres to model Charcot-Marie-Tooth disease. Her expertise spans molecular biology, disease modeling, CRISPR-Cas9 technologies, induced pluripotent stem cells, hematopoietic biology, and flow cytometry/FACS. She is passionate about advancing gene therapy technologies to improve treatments for patients with genetic disorders.