Guang Qu MS, PhD

Dr. Guang Qu has served as Technical Director for the Clinical Vector Core Laboratory at The Children’s Hospital of Philadelphia, a world-class facility for clinical vector manufacturing. In his role there, he has led process development, striving to optimize product purity and yield. Guang has more than 15 years working experience in the gene therapy field, including six years in the biotechnology industry directing process development at Avigen, Inc. He developed several breakthrough techniques in adeno-associated virus (AAV) vector production and purification, including scalable purification methods for eight serotypes of AAV vectors and a patented column-based purification process capable of removing most of the empty capsids that are naturally formed during the AAV production process. In addition, he participated in the designing of two cGMP facilities for manufacturing gene therapy vectors and is intimately familiar with cGMP regulation and operation. Guang is a member of the American Society for Gene Therapy and served on the AAV National Reference Standard Working Group from 2003 to 2005. He received his B.S. from Liaoning General University and his M.S. from Academia Sinica, both in China, and his Ph.D. from The Ohio State University.