Dr. Barber’s research focuses on understanding the mechanisms of innate immunity to virus infection and malignant disease. Gaining insight into the innate immune process allows investigators to develop translational research comprising the design of novel vaccines and therapeutics to combat these diseases. One of the laboratory’s interests involves analyzing the function of interferons (IFNs), which can be produced in response to virus infection. The IFNs are secreted from the cell, and following interaction with specific cellular receptors, mediate their action by inducing the expression of numerous genes, many of which exert potent antiviral and antitumor activity.
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