Gijs Van Den Brink MD,PhD
Hepatology, Gastroenterology, Oncology, Immunology and Microbiology
Amsterdam, Noord Holland, Netherlands
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Dr.Den Brink is currently professor at University Of Amsterdam. He is specialized in Gastroenterology, Hepatology, Oncology, Immunology. His current research projects are ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response, Female hormones in colorectal cancer development, Disordered cellular communication in esophageal cancer, The role of Hedgehog signal transduction in epithelial homeostasis of the colon.
His publications are as follows:
Amos-Landgraf JM, Heijmans J, Wielenga MCB, Dunkin E, Krentz KJ, Clipson L, Ederveen AG, Groothuis PG, Mosselman S, Muncan V , Hommes DW, Shedlovsky A, Dove WF, van den Brink GR, Sex disparity in colonic adenomagenesis involves promotion by male hormones, not protection by female hormones. P NATL ACAD SCI USA 2014;111 (46):16514-16519.
Büller NVJA, Rosekrans SL, Metcalfe C, Heijmans J, van Dop WA, Fessler E, Jansen M, Ahn C, Vermeulen JLM, Westendorp BF, Robanus-Maandag EC, Offerhaus GJ, Medema JP, D'Haens GRAM, Wildenberg ME, de Sauvage FJ, Muncan V , van den Brink GR, Stromal Indian hedgehog signaling is required for intestinal adenoma formation in mice. GASTROENTEROLOGY 2015;148 (1):170-180.e6.
Heijmans J, van Lidth de Jeude JF, Koo BK, Rosekrans SL, Wielenga MCB, van de Wetering M, Ferrante M, Lee AS, Onderwater JJM, Paton JC, Paton AW, Mommaas AM, Kodach LL, Hardwick JC, Hommes DW, Clevers H, Muncan V , van den Brink GR, ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response. CELL REP 2013;3 (4):1128-1139.
Wildenberg ME, Vos ACW, Wolfkamp SCS, Duijvestein M, Verhaar AP, te Velde AA, van den Brink GR, Hommes DW, Autophagy Attenuates the Adaptive Immune Response by Destabilizing the Immunologic Synapse. GASTROENTEROLOGY 2012;142 (7):1493-+.
Muncan V , Heijmans J, Krasinski SD, Büller NV, Wildenberg ME, Meisner S, Radonjic M, Stapleton KA, Lamers WH, Biemond I, van den Bergh Weerman MA, O'Carroll D, Hardwick JC, Hommes DW, van den Brink GR, Blimp1 regulates the transition of neonatal to adult intestinal epithelium. NAT COMMUN 2011;2:452.
His publications are as follows:
Amos-Landgraf JM, Heijmans J, Wielenga MCB, Dunkin E, Krentz KJ, Clipson L, Ederveen AG, Groothuis PG, Mosselman S, Muncan V , Hommes DW, Shedlovsky A, Dove WF, van den Brink GR, Sex disparity in colonic adenomagenesis involves promotion by male hormones, not protection by female hormones. P NATL ACAD SCI USA 2014;111 (46):16514-16519.
Büller NVJA, Rosekrans SL, Metcalfe C, Heijmans J, van Dop WA, Fessler E, Jansen M, Ahn C, Vermeulen JLM, Westendorp BF, Robanus-Maandag EC, Offerhaus GJ, Medema JP, D'Haens GRAM, Wildenberg ME, de Sauvage FJ, Muncan V , van den Brink GR, Stromal Indian hedgehog signaling is required for intestinal adenoma formation in mice. GASTROENTEROLOGY 2015;148 (1):170-180.e6.
Heijmans J, van Lidth de Jeude JF, Koo BK, Rosekrans SL, Wielenga MCB, van de Wetering M, Ferrante M, Lee AS, Onderwater JJM, Paton JC, Paton AW, Mommaas AM, Kodach LL, Hardwick JC, Hommes DW, Clevers H, Muncan V , van den Brink GR, ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response. CELL REP 2013;3 (4):1128-1139.
Wildenberg ME, Vos ACW, Wolfkamp SCS, Duijvestein M, Verhaar AP, te Velde AA, van den Brink GR, Hommes DW, Autophagy Attenuates the Adaptive Immune Response by Destabilizing the Immunologic Synapse. GASTROENTEROLOGY 2012;142 (7):1493-+.
Muncan V , Heijmans J, Krasinski SD, Büller NV, Wildenberg ME, Meisner S, Radonjic M, Stapleton KA, Lamers WH, Biemond I, van den Bergh Weerman MA, O'Carroll D, Hardwick JC, Hommes DW, van den Brink GR, Blimp1 regulates the transition of neonatal to adult intestinal epithelium. NAT COMMUN 2011;2:452.
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