Gianfranco D. Alpini PhD

Dr. Gianfranco Alpini joined the Division of Gastroenterology and Hepatology in January 2019 as the Director of the Indiana Center for Liver Research (ICLR) and the inaugural John B. Hickam Professor of Medicine. Dr. Alpini was most recently the Dr. Nicholas C. Hightower Centennial Chair in Gastroenterology at Texas A&M College of Medicine, where he had been a member of the faculty since 1994. The research interests of the Alpini Lab also include determining the interactions that occur between cholangiocytes and other cell types (such as hepatocytes, hepatic stellate cells, and vascular endothelial cells) in the biliary microenvironment during both cholestasis and cholangiocarcinogenesis. The lab evaluates the various signaling mechanisms regulating the balance between cellular proliferation/cellular senescence and apoptosis.