Frederick M. Hughson PhD

Frederick M. Hughson is Professor of Molecular Biology, with an associated appointment in the Department of Chemistry. In 1984, Fred received a B.S. in Molecular Biochemistry and Biophysics from Yale. In 1990, he earned Ph.D. in Biochemistry from Stanford for work on protein folding with Robert L. (Buzz) Baldwin.

After postdoctoral work with Don Wiley at Harvard on the x-ray structure of influenza hemagglutinin in its activated, low-pH state, Fred joined the Princeton faculty in 1994. With the exception of a sabbatical at the Medical Research Council’s Laboratory of Molecular Biology in Cambridge UK, Fred has been at Princeton ever since. Current research in the Hughson lab focuses on the multidisciplinary application of diverse tools, but especially x-ray crystallography, to the study of two areas of cell biology – intracellular transport and bacterial cell-cell communication (quorum sensing).