Fay Kastrinos MD

Dr. Fay Kastrinos is an Associate Professor of Medicine at Columbia University Irving Medical Center. She serves as the Director of the Gastrointestinal Cancer High Risk and Prevention Clinic and the Muzzi Mirza Pancreatic Cancer Prevention and Genetics Program at the Herbert Irving Comprehensive Cancer Center.   

Dr. Kastrinos’ clinical and research interests focus on genetic risk stratification for the early detection and prevention of gastrointestinal cancers, notably colorectal cancer, and pancreatic cancer. She has led clinical studies aimed at screening and early detection of these cancers and in the development of clinical risk assessment tools for routine use by healthcare providers.  Dr. Kastrinos’ research related to genetic risk assessment and prediction for inherited cancer syndromes has led to significant clinical contributions in the field as it relates to optimizing strategies for the early detection and prevention of gastrointestinal malignancies. Dr. Kastrinos is involved in multiple national and international collaborations to improve genetic risk assessment and optimize surveillance strategies for inherited colorectal and pancreatic cancer. The research also spans the evaluation of novel biomarkers for early cancer detection as well as innovative cancer prevention modalities.     

Dr. Kastrinos has received grant support from the National Cancer Institute, American Cancer Society, and Columbia University’s CTSA for her investigation of risk assessment tools for the early identification of carriers of inherited cancer syndromes to promote cancer screening and prevention.  Dr. Kastrinos is also site-PI for NCI-funded studies that aim to improve the risk assessment and early detection of pancreatic cancer.  

Dr. Kastrinos trained in Internal Medicine at the University of Massachusetts and completed her Gastroenterology fellowship at Brigham and Women’s Hospital in Boston, MA. She received specialty training in clinical cancer genetics at Dana-Farber Cancer Institute during her fellowship and also obtained a Master’s Degree in Public Health from the Harvard T.H. Chan School of Public Health.  She is board certified in Gastroenterology.