Edward M. Behrens MD

Dr. Behrens' research program centers on the pathogenesis of Cytokine Storm Syndrome, a common pathologic endpoint of a heterogeneous group of initiating diseases. Cytokine Storm Syndrome results in multi-organ failure and a stereotypical immune response including increased serum ferritin and Interferon-gamma that leads to the organ failure itself.

He is specifically interested in dissecting the initiating, propagating, and regulatory factors that determine the pace and outcome of the cytokine storms. This is accomplished using a number of different murine models including perforin deficient mice, repeated TLR9 agonist injections, and other murine systems of systemic inflammation. The ultimate goal of these investigations is to improve the lives of patients that suffer from Cytokine Storm Syndrome by developing strategies for treatment and prevention.