Dian Su PhD

Dian is a Scientist in Drug Metabolism and Pharmacokinetics (DMPK) at Genentech. Her primary interest is focused on small molecule drug metabolism in discovery stage. In this role, her responsibilities include: 1) developing new generation assays for metabolite identification (Met ID) to improve the throughput and tackle challenges associated with drug metabolite ID; 2) exploring deep understanding of metabolite formation and biological impact, and establish structure−activity relationship (SAR) for drug metabolites. Prior to Feb 2017, Dian was a scientist in the BioAnalytical Sciences-Assay Development & Technology Department (BAS-ADT) at Genentech. In this role, her major interest lied in biotransformation and bioanalysis of antibody-drug conjugates (ADCs) using immunoaffinity capture, high-pressure liquid chromatography (HPLC) and mass spectrometry (MS) strategies.

Before joining Genentech in 2012, Dian held a postdoctoral position at the NIH Proteomics Research Resource for Integrative Biology in Pacific Northwest National Laboratory. She earned her Ph. D. in Chemistry in 2010 from Washington University in St. Louis under the direction of Michael L. Gross and John-Stephen A. Taylor. Dian has published her recent research on ADC biotransformations in Analytical Chemistry and Bioconjugate Chemistry. Her earlier research was published in multiple journals including J. Am. Chem. Soc. (JACS) and Proc. Natl. Acad. Sci. (PNAS). She has served as a co-chair for conference workshops and peer reviewer for several scientific journals.