Dario A Vignali BSc, PhD

Dr. Vignali began his academic career at St. Jude Children’s Research Hospital where he became Vice Chair and Full Professor. In 2014, Dr. Vignali moved to the University of Pittsburgh, School of Medicine to become Vice Chair and Professor of Immunology, Co-Leader of the Cancer Immunology Program and Co-Director of the Tumor Microenvironment Center.

Dr. Vignali’s research focuses on gaining a better understanding of the inhibitory mechanisms, including inhibitory receptors and regulatory T cells, that limit anti-tumor immunity in cancer patients. I also have discovery-based programs aimed at identifying novel targets for therapeutic intervention. I am also working with UPCI scientists and clinicians to facilitate the translation of novel therapeutic modalities with a focus on immunologically impacted solid tumors (primarily head and neck, melanoma, lung, pancreatic cancer). My UPCI leadership efforts are directed toward providing a bridge between basic and transitional cancer immunology.