Cyril Benes, PhD, leads the Center for Molecular Therapeutics at the Mass General Cancer Center, which conducts cutting-edge research on the design and application of personalized therapies for cancer. In collaboration with the Wellcome Trust Sanger Institute in the United Kingdom, the Benes Laboratory is exploring how specific genetic changes in tumor cells influence sensitivity to anti-cancer drugs.
Dr. Benes and his colleagues have pioneered the use of a high-throughput robotic platform to screen more than 1,000 human cancer cell lines in the laboratory against a wide range of known and potential cancer therapies. Among the goals are identifying specific biological markers on tumor cells that will help doctors choose the best targeted therapy for each patient, and discovering new treatment options for many different cancers.
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