Dr. He is the John T. Wilson Distinguished Service professor of chemistry, biochemistry, and molecular biology, and director of the Institute for Biophysical Dynamics at the University of Chicago. Chuan He's group discovered the first RNA demethylase that reverses the most prevalent internal messenger RNA methylation in mammalian cells. He is working toward revealing biological functions and understanding pathways and mechanisms associated with reversible RNA methylation in various organisms. He also develops and applies enabling technologies to understand active DNA demethylation in modulating gene expression.