Chris Sander PhD
Cell and Developmental Biology
New York, New York, United States of America
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Dr. Sander combines theory and experiment to develop predictive models of biological systems and build tools that translate genomic data into biomedical knowledge and practice.
Lab members and their collaborators infer quantitative models of signaling in normal or cancer cells by performing combinatorial perturbation experiments with rich molecular readout using perturbants, such as targeted drugs, and then optimizing predictive accuracy and model simplicity. The resulting computational models can be used to design combinatorial interventions for investigational or therapeutic purposes, identify novel drug synergies, discover the specificity spectrum of drugs or redesign cellular circuits for synthetic biology.
Lab members and their collaborators infer quantitative models of signaling in normal or cancer cells by performing combinatorial perturbation experiments with rich molecular readout using perturbants, such as targeted drugs, and then optimizing predictive accuracy and model simplicity. The resulting computational models can be used to design combinatorial interventions for investigational or therapeutic purposes, identify novel drug synergies, discover the specificity spectrum of drugs or redesign cellular circuits for synthetic biology.
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