Caterina Giannini

My research focuses on tumors of the central and peripheral nervous system and the pathologic features predictive of patients outcome. My interest is in correlative studies to determine the clinical significance of histologic and genetic variables in brain tumor tissue, in particular in the setting of clinical trials of patients with gliomas. I am responsible for the Mayo Clinic Brain Cancer SPORE Tissue Core for the collection of fresh and fixed brain tissues for research; the Brain SPORE Tissue Core also supports high-throughput tissue microarray construction, laser capture microdissection, immunohistochemistry, FISH, in situ hybridization and a variety of other techniques. A recent research development, in collaboration with the Mayo lymphoma SPORE investigators, has been the study of primary CNS malignant lymphoma cytogenetics, including low and high grade B-cell lymphomas.