Carlo Maria Croce MD

Carlo Maria Croce is working as a Chair and, Professor at Ohio State University. Renowned for his investigations of cancer pathogenesis, Dr. Croce has provided valuable insights into the underlying, genetic basis of cancer onset. His research has established genetic links to a variety of cancers including Burkitt’s lymphoma, T-cell lymphoma, and acute leukemia. His discoveries have shown that chromosomal abnormalities such as translocations are capable of contributing to both cancer initiation and progression.

Carlo Maria Croce In addition to his studies involving genes such as ALL1 and TCL1, Dr. Croce was the first investigator to discover and sequence BCL2. He later defined a role for this protein in various lymphomas such as follicular lymphoma. More recently, Dr. Croce’s work has centered on understanding the role of micro RNAs in cancer pathogenesis. His research has proved that particular micro RNAs have the potential to exhibit either oncogenic or tumor-suppressive properties. While heavily involved in research, Dr. Croce also served as editor-in-chief for Cancer Research (1990-1999).