Cameron Dezfulian

I am interested in ways of reducing cerebral and cardiac injury resulting from cardiac arrest. In the lab, I have developed mouse and rat models of cardiac arrest to study the effects of nitrite, an ischemic reservoir for nitric oxide and potent S-nitrosating agent, in achieving this organ protection. I am working to translate promising findings from bench to bedside and we have begun a phase I study of nitrite in cardiac arrest survivors. Clinically, I am interested in aspects of post-resuscitation care which may affect these organ injuries. Current projects examine the role of oxygen, hemodynamic support and temperature control in mitigating cerebral and cardiac injury. I am also a member of the UPMC post-cardiac arrest service in charge of cardiac arrest post-resuscitation quality improvement at UPMC Mercy.