C. Buddy Creech
Dr. Creech and his colleagues seek to understand the clinical and molecular epidemiology of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA). The work of the group focuses on describing the changing dynamics of nasal colonization with CA-MRSA and on how these isolates differ from those that cause invasive staphylococcal disease. In addition, the laboratory studies the adaptive response to infection, focusing on the serum antibody response to critical staphylococcal antigens. Work in the Vanderbilt Vaccine Research Program, where Dr. Creech serves as Associate Director, is directed towards clinical trials of vaccines and therapeutics, including monoclonal antibodies targeting S. aureus, influenza vaccine trials, and malaria vaccines. Clinical investigations in the group are led by Gayle Johnson, RN, Shanda Phillips, RN, Sheana Fox, RN, and others within the Vanderbilt Vaccine Research Program. The laboratory is directed by Ms. Elizabeth Saye, who has extensive experience in microbiology, molecular epidemiology, and human immunology. Dr. Creech graduated cum laude from Vanderbilt University before attending the University of Tennessee College of Medicine. After graduating with high honors, he joined the pediatric housestaff at Vanderbilt Children's Hospital and was Chief Resident in Pediatrics in 2002. During his pediatric infectious diseases fellowship at Vanderbilt Children's Hospital, Dr. Creech completed the Masters in Public Health degree and became part of the Vanderbilt Clinical Research Scholars (VCRS) Program, a competitive NIH K12 award given to young investigators at VUMC. He joined the faculty in July 2006 as Assistant Professor of Pediatric Infectious Diseases and now serves as Associate Director of the Vaccine Research Program and Co-Director of the Pediatric Infectious Diseases Fellowship.