Dr Humbel's research focuses on sample preparation for optimal, life-like imaging of biological objects in the electron microscope. His main interests are preparation methods based on cryo-fixation. From here hybrid follow-up methods like freeze-substitution or freeze-fracture are used. Since a couple of years he is shifting to imaging modes and was lucky enough to be close to the cradle of the integrated light-electron microscope developed by his colleagues in Utrecht. In Lausanne, the main development lines are correlative microscopy and FIB-SEM tomography.
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