Dr. Bruce Blough, Ph.D., conducts synthetic medicinal chemistry research at RTI. The current focus of his laboratory is novel and atypical biogenic amine releasers, including hybrid releasers/uptake inhibitors and partial releasers. The laboratory is also researching natural products, particularly compounds that modulate microbial growth and signaling. Dr. Blough joined RTI in 1990. Over the years, he has worked on teams that have progressed products to IND-ready and phase 1 clinical trial, such as tropanes and methamphetamine haptens. His past projects aimed at developing novel therapeutics include Dopamine transporter inhibitors.